CD Skripsi

Uji Toksisitas Dan Aktivitas Antioksidan Tiga Jenis Gulma Potensial Sebagai Tumbuhan Obat Dengan Metode Bslt (Brine Shrimp Lethality Test) Dan Dpph (2,2-Difenil-1- Pikrilhidrazil)

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ABSTRACT
The three potential weeds, Asystasia gangetica, Artemisia vulgaris and Ruellia tuberosa, tend to be ignored because they are considered as plants that live in unwanted or disturbing places. Weed plants contain antioxidant compounds as such useful for environment change adapt. However, phytochemical characterization data as basic data in the development of this plant as a medicinal material is not yet available. Therefore, it is necessary to conduct research on toxicity tests and antioxidant activity on three weeds. The study was conducted in vivo with BSLT method using Artemia salina larvae to obtain half-maximal lethality concentration (LC50) and with DPPH method using microplate reader to obtain Inhibition concentration (IC50). The results showed that the leaf and stem extracts of Artemisia vulgaris mixed solvent methanol, ethyl acetate and n-hexane showed the character of cytotoxic ability with LC50 values of 0.0342 ppm, 0.3874 ppm and 17.661 respectively and the leaf and stem extracts of Ruellia tuberosa mixed solvent methanol, ethyl acetate and n-hexane LC50 values of 0.0584 ppm, 2, 1514 ppm and 3.9810 while extracts of leaves and stems of mixed Asystasia gangetica methanol solvent, ethyl acetate and n-hexane showed low toxic and non-toxic character respectively 336.584 ppm, 2127.93 ppm and 3595.48 ppm, the cause of the low LC50 value on Asystasia gangetica caused at the time of extracting the solvent ethyl acetate and n-hexane can not dissolve in water. The results of testing the antioxidant activity of the three weeds in mixed leaf and stem extracts of Asystasia gangetica methanol, ethyl acetate and n-hexane solvents are 110.9 ppm, 4127.7 ppm and 19235, 4 ppm, IC50 values in mixed leaf and stem extracts of Artemisia vulgaris methanol, ethyl acetate and n-hexane solvents are 148 ppm, 650 ppm and 3122.2 ppm. The IC50 values of leaf and stem extracts of Ruellia tuberosa mixture of methanol, ethyl acetate and n-hexane solvents are 17 ppm, 178012.1 ppm and 288764.8 ppm, indicating that the three weeds with methanol, ethyl acetate and n-hexane solvents have not shown potential as antioxidant activity.
Key findings: Antioxidants, BSLT, cytotoxicity, DPPH, weeds.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

1903124088

Penerbit

Pekanbaru : Universitas Riau - FMIPA - Biologi., 2023

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

1903124088

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

BIOLOGI

Info Detail Spesifik

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Pernyataan Tanggungjawab

TIAR

Versi lain/terkait

Lampiran Berkas

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