LBKURCC40 is endophytic fungi which was isolated from orange flowering dahlia tubers of plants from outside Padang, West Sumatra. Identification by Lorenita (2013), Hendris (2015) and preliminary studies showed conflicting results, indicating that the isolate was not pure. Therefore purification and reidentification of LBKURCC40 was done to establish its correct identity. This study conducted s…
Macaranga bancana (Euphorbiaceae) is known as "mahang" which is widely distributed in Indragiri Hulu, Riau Province and it is also believed to posses medicinal properties, such as anti-infection agents. This study was to isolate and characterize the secondary metabolites, and their antimicrobial activity from n-hexane and ethyl acetate extracts as well as their fractions. Extraction techniques …
Mempening (Lithocarpus bancanus) is a plant from Fagaceae family found in the Talang Mamak tribe in Kelayang District, Indragiri Hulu Regency, Riau Province. This plant is usually used by the tribe as a medicine for several diseases such as pain relief and inflammation. Some species of this genus have been reported to contain various secondary metabolites, including terpenoids, steroids and fla…
Red miana (Coleus hybridus) is one of species in genus Coleus, family Lamiaceae which is a potential source of traditional medicines. The purpose of this study is to isolate, examine biological activities, including antioxidant and toxicity from secondary metabolites of the plant. As much as 13.7 kg C. hybridus was extracted with maceration method by using methanol and separated into two fracti…
A novel bimetallic with carboxylic anchoring ligands and thiocyanate connecting ligands from the ruthenium bipyridyl complex and the tungsten carbonyl complex was synthesized. The function of anchoring ligand is to facilitate covalent bond with semi conductor surface. The black bimetallic complex solid product was soluble in polar protic solvents. The ligands and metal complexes were characteri…
Titanium dioxide is one of the most investigated materials for photoelectrochemical (PEC) water splitting. However, TiO2 has a wide band gap of approximately 3.2 eV, which limits its absorption energy to UV only, and the photoexcitation products (i.e., electron and hole) easily recombine. Developing a composite with other semiconductor materials is one of the efforts for improving the performa…
Magnetite (Fe3O4) nanoparticles is a magnetic nanomaterial that have potential properties to be applied as drug delivery. The purpose of this study was to determine the influence of time and temperature synthesis of magnetite characteristics and determine its crystal growth kinetics model with Ostwald ripening model approach. Magnetite nanoparticles synthesized from FeCl3, citrate, urea and pol…
The objectives of the research are to synthesize manganese oxide catalysts by using KMnO4 and H2C2O4 via reflux method with and without the calcination and to investigate the performance of the catalysts for the degradation of methylene blue. The products, birnessite-type octahedral layer manganese oxides have been succesfully synthesized with different reflux times. The precipitate solid pro…
Seven Flavonol derived of 2'-hydroxycalone are 2- (2-methoxyphenyl) -3-hydroxy-4H-kromen-4-on (F4), 2- (3-methoxyphenyl) -3-hydroxy-4H-kromen-4-7 on (F5), 2- (4-methoxyphenyl) -3-hydroxy-4H-kromen-4-on (F6), 2- (2,3-dimetoksifenil) -3-hydroxy-4H-kromen-4-on (F7), 2- (2,5-dimethoxyphenyl) -3-hydroxy-4H-kromen-4-on (F8), 2- (3,4-dimetoksifenil) -3-hydroxy-4H-kromen-4-on (F9) and 2- (3,4,5-dimetho…
Fusarium oxysporum is one of endophytic microbes isolated from dahlia tuber (Dahlia variabilis) which has the ability to produce secondary metabolites. The purpose of this research was to find the optimum condition of fermentation to producing secondary metabolites. Corn, potato, and sweet potato and combination of them with particle size of 80 mesh were used as carbon sources to produce second…
Pyrazoline compounds known as the azole group which is consist of oxazole, thiazole, imidazole and pyrazole groups. Pyrazoline is obtained by reacting chalcone with phenyl hydrazine or hydrazine hydrate. Pyrazoline synthesis is carried out using microwave irradiation methods which in this case use microwave oven. Synthesis of pyrazoline contain functional groups obtained from chalcone. Function…
Bagasse is organic solid waste left over from industrial sugar and cane juice drinks that have not been utilized properly. High cellulose content in bagasse can be used as raw material for composting. Making compost can be accelerated by adding bioactivators. This study aimed to analyze the ability of Trichoderma (LBKURCC1 and LBKURCC2) and Pseudomonas (LBKURCC54 and LBKURCC59) as bioactivators…
The objectives of the research are to synthesize manganese oxide catalysts by using KMnO4 and citrat acid via reflux method and to investigate their catalytic activities for the degradation of methylene blue. The resulting products obtained through the variation of reflux time (1,3,6,9 and 12 hours) are birnessite-type octahedral layered manganese oxides. The catalysts were then calcined up to …
Manganese oxide containing with mixture phases was obtained by the reaction between KMnO4 and glucose using the sol-gel method with the mole ratio of 2:3. The Characterization of the oxide using X-ray diffraction showed crystalline peaks of the three-type phases of manganese oxide; manganosite (55.4%); hausmanite (31.9%) and birnessite (12.7%). The morphology results from the manganese oxide us…
Curcumin and its analogs are important secondary metabolites. Some analog showed various biological activities including antiinflammatory, anticancer and antioxidant. This research has successfully synthesized curcumin ethyl 2 - ((3E, 5E) -3,5-bis ((E) -4-methoxy benzylidene) -4-oxopiperidine-1-yl) acetate, ethyl 2 - (( 3E, 5E) -3,5-bis ((E) -2-methoxy benzyliden) -4-oxopiperidine-1-yl) acetate…
A study has been conducted to synthesize analog of curcumin with base catalyzed condensation of 4-piperidone hydrochloride with substituted benzaldehyde under reflux led the formation of mono-carbonyl curcumin. The synthesized curcumin were further reacted with benzosulphonyl chloride by nucleophilic substitution of –NH group to afford 3,5-bis((E)-2-metoksi benziliden)-1-(fenilsulfonil)piper…
Coleus scutellarioides is one of medicinal plants which has been used to treat various diseases in Indonesia. In this study, the fresh leaves of this species were extracted, with various solvents (methanol, ethyl acetate, dichloromethane, and n-hexane). All extracts, n-hexane fractions and pure isolated compounds (CS-H01 and CS-H02) were tested for antioxidant activity using DPPH radicals and t…
Plectranthus amboinicus (Lour.) is a perennial plant belonging to the family Lamiaceae which have widely used in traditional herbal medicine. In the present study, the extracts of the leaves of P. amboinicus by different solvent were evaluated for their antioxidant and antibacterial properties. The fresh leaves of the plant were extracted using methanol subsequently fractionated using n-hexane …
Endophytes are organisms living in plants tissue which can produce antimicrobial compounds as the host. Production of chemical compounds by fermentation is influences by media composition. Fermentation media is the main component to produce industrial compounds. The objective of this research was to investigate optimal media consisted of widely available natural compounds in order to produce an…
Garcinia mangostana fruit hull contain antioxidant compounds. A concentrated extract of Garcinia mangostana fruit hull in 50% ethanol and 0.05M NaOAc pH 5,5 buffer, had an in vitro antioxidant activity (IC50) of 47.3 μg/mL, when measured by the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method. However, this concentrated extract was toxic when applied to keratinocyte cells, with IC50 of μg/mL.…