ABSTRACT The incidence of short toddlers or what is known as stunting is one of the current issues of particular concern in developing countries, especially Indonesia. Breastfeeding mothers take a major role in providing nutritious food intake and ensuring that the child’s health is maintained. Therefore, this study aims to identify risk factors for stunting from the aspect of breastfeeding…
ABSTRACT The vast amount of medical literature is published and doctors are encouraged to read more than one research report every half hour. Meanwhile, doctors have limited time to get the latest information amidst their busy lives. On the other hand, doctors and health care practitioners receive many questions regarding decision making in patient care. Evidence Based Medicine (EBM) is th…
ABSTRACT The use of digital histology atlases as an alternative self-learning medium can assist students in overcoming difficulties in studying histology materials. The quality of learning media is a key factor in the success of education. Therefore, evaluating learning media using usability assessment is necessary as an important parameter to assess the quality of the created learning med…
ABSTRACT Chronic kidney disease is a damaged kidney with abnormalities within the kidney structure and function that lasts for ≥3 months, based on the pathological abnormalities or other signs of damage accompanied by a decreasing Glomerular Filtration Rate with a value of 120 mg/dL, 56.3% had creatinine levels of >8 mg/dL, 58.3% had normal-category sodium levels, and 54.2% had normal-catego…
ABSTRACT Introduction: Anxiety and depression can be found in chronic kidney disease (CKD) patients undergoing hemodialysis (HD) and affect motivation to undergo HD. These can be related to certain factors, namely gender, age, occupation, length of HD. Objective: To determine the prevalence of anxiety and depression symptoms in CKD patients undergoing HD and associated factors. Methods: This c…
ABSTRACT Cervical carcinoma is an epithelial malignancy in the cervix, primarily caused by HPV infection. The main HPV types responsible for cervical carcinoma are HPV-16 and HPV-18. Between these two infections, there are differences in distribution and prognosis in cervical carcinoma. This study identifies differentially expressed genes between HPV-16 and HPV-18 infections based on their mol…
ABSTRACT Rheumatoid arthritis is a progressive autoimmune disease with chronic inflammation that can cause pain, swelling, and stiffness in the joints, especially in the hands, feet, and knees. This study aims to determine the clinical and laboratory features in patients with rheumatoid arthritis at the Arifin Achmad Regional General Hospital from 2019-2022. The research method was cross-sec…
ABSTRACT Malaria is one of the major life-threatening problems in Indonesia caused by the Plasmodium parasite. Indonesia is the country with the most malaria cases in Asia after India. One of the provinces in Indonesia that is still trying to control the transmission of malaria is Riau Province. This study aims to describe the distribution of malaria in 12 districts/cities of Riau Province b…
ABSTRACT Endometrial carcinoma is the most common malignancy in the deepest part of the uterus (endometrial). Failure of the DNA repair systems such as Mismatch repair (MMR) will occur microsatellite instability (MSI) if it do not repaired properly and is associated with endometrial carcinoma. MSH3 is one of the MMR genes which plays a role in the DNA repair system. The aim of this study is …
ABSTRACT The incidence of human immunodeficiency virus (HIV) infection may lead to neurological impairment, causing cognitive and behavioral disorders. Cognitive impairment in people living with HIV is frequently associated with various factors such as age, level of education, antiretroviral therapy utilization, and opportunistic infections. This study aims to determine the factors associated …
ABSTRACT Endometrial carcinoma (EC) is a malignancy of the deepest epithelial cells layer of the uterine. Failure of DNA repair system such as mismatch repair (MMR) is a predisposing factor of EC. The MutS homolog 3 (MSH3) gene is one of the MMR genes that will correct microsatellite instability (MSI) which is reported in EC. The aim of this study is to investigate the expression of MSH3 gen…
ABSTRACT Fatty liver is highly prevalent in type 2 diabetes mellitus (T2DM), where the mechanism is related to obesity and insulin resistance in T2DM. Fatty liver is characterized by the accumulation of lipids in the liver (steatosis) in response to excessive triglyceride synthesis in hepatocytes and may be related to intestinal microbiota disturbances. The prebiotic inulin is a naturally occ…
ABSTRACT Ischemic stroke is a clinical symptom in the form of a functional disorder of the brain and occurs suddenly with clinical signs and symptoms, both partial and complete, that last 24 hours or more due to blockage of blood vessels to the brain. One of the clinical symptoms of ischemic stroke is dysphagia (swallowing disorders). This symptom is quite worrying in ischemic stroke patient…
Type 2 diabetes mellitus (DM) is a metabolic disorder predisposing to cardiovascular disease (CVD) due to atherosclerosis. Atherosclerosis is chronic inflammatory reaction characterized by accumulation of lipids in the wall of arteries. This study aims to analyze the effect of inulin extract of dahlia tuber on the histopathological in the thoracic aorta of type 2 DM rats. Inulin be able to decr…
ABSTRACT Urinary tract infection (UTI) is a disease that is caused by microorganism growth in urinary tract. UTI is commonly found in elderly. This disease is increasing due to urinary tract function regression such as urethra sphincter weakening and bladder volume decreasing. Urine dipstick examination can be an early screening test for UTI. In this study, the indicator that can be measured…
ABSTRACT Type 2 diabetes mellitus (type 2 DM) is a metabolic disorder caused by impaired insulin function and insulin deficiency. Inflammation of pancreatic islets (insulitis) has been known to be one of the etiopathologies of type 2 DM. The aim of this study was to analyse the effect of inulin extract of dahlia tuber as a potential anti-inflammatory agent against insulitis in type 2 DM rats. …
ABSTRACT Urine dipstick is a test strip that chemically detects leukocyte, nitrite, urobilinogen, protein, pH, erythrocyte, specific gravity, ketone, bilirubin, and glucose in urine. This strip is usually used for kidney and urinary tract disease and also metabolic disease health screening. In elderly, flank pain can direct a diagnose to kidney and urinary tract disease such as urolithiasis a…
ABSTRACT Human Immunodeficiency Virus (HIV) is still a global health problem, including in Indonesia. Nervous disorders are one of the complications arising from antiretroviral therapy (ARV) and opportunistic infections. One of the nervous disorders that can occur in HIV/AIDS patients is sleep disorders. There are several factors that can be related to sleep quality in HIV/AIDS patients such…
Background: The HIV/AIDS infection can attack the central and peripheral nervous systems, leading to various neurological complications. Risk factors that can cause neuropathic disorders include age, gender, duration of diagnosis, clinical stage of HIV, CD4 count, viral load, ARV therapy, and opportunistic infections. The manifestations of neuropathic disorders are neuropathic pain, numbness,…
ABSTRACT The activity of vitamin D is controlled by the Vitamin D Receptor (VDR), which is located in many body cells. Vitamin D is often associated with obesity. Obesity based on fat distribution is known as central obesity which can be influenced by many factors, such as environmental and genetic factors. The genetic factor suspected to be a risk factor for obesity is the polymorphism of t…