ABSTRACT Endometrial carcinoma (EC) is a malignancy of the deepest epithelial cells layer of the uterine. Failure of DNA repair system such as mismatch repair (MMR) is a predisposing factor of EC. The MutS homolog 3 (MSH3) gene is one of the MMR genes that will correct microsatellite instability (MSI) which is reported in EC. The aim of this study is to investigate the expression of MSH3 gen…
ABSTRACT Fatty liver is highly prevalent in type 2 diabetes mellitus (T2DM), where the mechanism is related to obesity and insulin resistance in T2DM. Fatty liver is characterized by the accumulation of lipids in the liver (steatosis) in response to excessive triglyceride synthesis in hepatocytes and may be related to intestinal microbiota disturbances. The prebiotic inulin is a naturally occ…
ABSTRACT Ischemic stroke is a clinical symptom in the form of a functional disorder of the brain and occurs suddenly with clinical signs and symptoms, both partial and complete, that last 24 hours or more due to blockage of blood vessels to the brain. One of the clinical symptoms of ischemic stroke is dysphagia (swallowing disorders). This symptom is quite worrying in ischemic stroke patient…
Type 2 diabetes mellitus (DM) is a metabolic disorder predisposing to cardiovascular disease (CVD) due to atherosclerosis. Atherosclerosis is chronic inflammatory reaction characterized by accumulation of lipids in the wall of arteries. This study aims to analyze the effect of inulin extract of dahlia tuber on the histopathological in the thoracic aorta of type 2 DM rats. Inulin be able to decr…
ABSTRACT Urinary tract infection (UTI) is a disease that is caused by microorganism growth in urinary tract. UTI is commonly found in elderly. This disease is increasing due to urinary tract function regression such as urethra sphincter weakening and bladder volume decreasing. Urine dipstick examination can be an early screening test for UTI. In this study, the indicator that can be measured…
ABSTRACT Type 2 diabetes mellitus (type 2 DM) is a metabolic disorder caused by impaired insulin function and insulin deficiency. Inflammation of pancreatic islets (insulitis) has been known to be one of the etiopathologies of type 2 DM. The aim of this study was to analyse the effect of inulin extract of dahlia tuber as a potential anti-inflammatory agent against insulitis in type 2 DM rats. …
ABSTRACT Urine dipstick is a test strip that chemically detects leukocyte, nitrite, urobilinogen, protein, pH, erythrocyte, specific gravity, ketone, bilirubin, and glucose in urine. This strip is usually used for kidney and urinary tract disease and also metabolic disease health screening. In elderly, flank pain can direct a diagnose to kidney and urinary tract disease such as urolithiasis a…
ABSTRACT Human Immunodeficiency Virus (HIV) is still a global health problem, including in Indonesia. Nervous disorders are one of the complications arising from antiretroviral therapy (ARV) and opportunistic infections. One of the nervous disorders that can occur in HIV/AIDS patients is sleep disorders. There are several factors that can be related to sleep quality in HIV/AIDS patients such…
Background: The HIV/AIDS infection can attack the central and peripheral nervous systems, leading to various neurological complications. Risk factors that can cause neuropathic disorders include age, gender, duration of diagnosis, clinical stage of HIV, CD4 count, viral load, ARV therapy, and opportunistic infections. The manifestations of neuropathic disorders are neuropathic pain, numbness,…
ABSTRACT The activity of vitamin D is controlled by the Vitamin D Receptor (VDR), which is located in many body cells. Vitamin D is often associated with obesity. Obesity based on fat distribution is known as central obesity which can be influenced by many factors, such as environmental and genetic factors. The genetic factor suspected to be a risk factor for obesity is the polymorphism of t…
ABSTRACT ARI is a type of infectious disease that occurs in the respiratory tract. ARI often occurs in toddlers even be the cause of toddlers mortality today. The purpose of this study was to know the correlation of birth weight, nutritional status, exclusive breastfeeding, immunization status, exposure to cigarette smoke and residencial density by ARI incidence. This research method using a…
ABSTRACT Opportunistic intestinal protozoa are protozoa that infect humans when the body's defense system decreases (immunocompromise). Opportunistic intestinal protozoan infections were found in immunocompromised patients and have been reported to infect children. Cryptosporidium sp, Cyclospora sp, Cystoisospora belli, and Blastocystis hominis have been identified to cause infection. This res…
ABSTRACT DETECTION OF Blastocystis hominis IN STOOL ORPHAN PEKANBARU USING THE CULTURE METHOD By Muhammad Devlin Ridan Hamdan Blastocystis hominis is an intestinal protozoan that can infect humans and animals. It is widely distributed and transmitted via the fecal-oral route. The incidence of Blastocystis hominis is high in developing countries, with poor personal hygiene practices, c…
ABSTRACT A DESCRIPTIVE STUDY TO ASSES PSYCHOLOGY OF ISOLATED ANTERIOR CRUCIATE LIGAMENT INJURY PATIENTS POST-RECONSTRUCTION SURGERY AT ARIFIN ACHMAD HOSPITAL PEKANBARU 2018–2020 PERIOD TUBAGUS ZUFAR WAHID Background: Anterior cruciate ligament injuries are caused by excessive resistance to anterior displacement of the tibia against the femur, causing injuries that can have an impact on the…
ABSTRACT EXPRESSION OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) ATHEROSCLEROTIC RATS AORTA AFTER ADMINISTRATION OF EXTRACT OF MANGROVE FRUIT (Sonneratia alba) By : Fitri Tio Arta Sonneratia alba is a plant that is high in antioxidants such as alkaloids, phenolics, flavonoids, tannins, steroids, terpenoids and saponins. Antioxidants has been proven can prevent foam cell formation, in which…
ABSTRACT THE RELATIONSHIP OF MATERNAL KNOWLEDGE WITH BEHAVIOR TOWARDS ANTIBIOTIC USE IN TODDLER PATIENTS WITH ACUTE RESPIRATORY INFECTIONS (ARI) IN SEVERAL HEALTH CENTERS IN PEKANBARU CITY By HUMAIRA LUQYANA A high incidence of infection followed by irrational use of antibiotics can lead to antibiotic resistance. Acute Respiratory Infection Disease (ARI) is one of the diseases that oft…
ABSTRACT PROFILE OF CASE OF DISASTER VICTIM IDENTIFICATION HANDLING IN MEDICINE AND HEALTH AT THE BHAYANGKARA HOSPITAL IN PEKANBARU By Rofiah Disaster victim identification (DVI) is a method that describes a step in the process of determining the identity of victims who died as a result of a large-scale disaster that still requires scientific explanation and follows Interpol standards. …
ABSTRACT THE PATTERNS OF BACTERIA AND ANTIBIOTICS SENSITIVITY ON POST-ODONTECTOMY SILK THREADS BACTERIA AT ARIFIN ACHMAD HOSPITAL, RIAU By FARHAN HADI Impacted teeth refers to a condition in which one's teeth are buried or not erupting (either a part of or the whole teeth) during normal eruption period. The treatment for it called odontectomy. Silk threads are used for suturing in the afore…
ABSTRAK PREVALENSI TOKSOPLASMOSIS BERDASARKAN IgG ANTI Toksoplasma gondii PADA LAKI-LAKI DENGAN GANGGUAN ANALISIS SPERMA Oleh Mokhamad Raihan Eka Putra Toksoplasma gondii adalah parasit protozoa intraseluler yang menyebabkan toksoplasmosis. Penularan toksoplasmosis bisa terjadi melalui tiga jalur penularan mendasar, yaitu makanan yang dimakan, penularan dari hewan ke manusia, dan dari ibu k…
SUMMARY ROMMY YORINDA PUTRA, NIM. 1810246536 Difference Mean Neutrophil Lymphocyte Ratio (NLR) in Preeclampsia, supervised by Zulmaeta and Elda Nazriati. Preeclampsia is a pregnancy-specific syndrome characterized by the presence of new-onset hypertension and proteinuria after 20 weeks' gestation in women who previously had normal blood pressure. An exaggerated systemic inflammatory resp…