Rukam is one of the species of Flacourtiaceae which is widely distributed in Sumatra and used as anti-diarrhea and anti-inflamatory ethnomedicine. Several species of this genus were reported to have antioxidant and cytotoxic activity. Phytochemical analysis showed that the leaf of rukam contained of flavonoids, saponins, fenolic, terpenoids and steroids. This study was aimed to isolate secondar…