CD Skripsi
Uji Aktivitas Senyawa Flavonoid Sebagai Antibakteri Dari Mangga Liar Mangifera Magnifica Terhadap Beberapa Bakteri Patogen
Unwise use of antibiotics can cause resistance to pathogenic bacteria, so it is necessary to find new sources of antibiotics that are more effective in dealing with pathogenic bacteria that are becoming resistant to antibiotics. Mangifera magnifica is reported to contain phenolic and flavonoids compounds. Flavonoids can function as antimicrobial ingredients by forming complex bonds with cell walls and damaging cell membranes. This study aims to test the antibacterial ability of flavonoids compounds of Mangifera magnifica leaves against pathogenic bacteria Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa which are known to be resistant to several antibiotics by looking at the inhibition zone formed. The antibacterial ability test of flavonoids compounds of Mangifera magnifica leaves against pathogenic bacteria Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa was carried out by varying the concentration of extracts, 15%, 10% 5% and 1% using disc diffusion and well diffusion methods. The results obtained showed the presence of an inhibition zone with the largest inhibition zone obtained from the 15% concentration variation of each test bacteria, in the Staphylococcus aureus test bacteria was 13.32 mm, Staphylococcus epidermidis was 13.24 mm, and Pseudomonas aeruginosa was 8.05 mm. The zone of inhibition formed indicates that flavonoid compounds of Mangifera magnifica leaves can inhibit the growth of Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa bacteria.
Key findings : Antibacterial, Flavonoids, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis.
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