CD Skripsi
Pengaruh pemberian ekstrak buah seri (Muntingia calabura) terhadap sgpt pada tikus wistar yang diberikan diet tinggi lemak
Non-Alcoholic Fatty Liver (NAFL) is a stage of liver fat accumulation before
Non-Alcoholic Steatohepatitis (NASH), which occurs due to excessive fat
buildup in the liver. One factor that can contribute to this disease is the
consumption of high-fat foods without adequate intake of other nutrients like
carbohydrates and proteins. Various efforts are being made to prevent NAFL,
including research on medicinal plants, one of which is the cherry fruit
(Muntingia calabura), known for its potential to prevent this disease. The cherry
fruit has antioxidant and anti-inflammatory effects, demonstrated by its content
of flavonoids, alkaloids, saponins, and tannins. The aim of this research is to
determine the effect of cherry fruit extract on Serum Glutamic Pyruvic
Transaminase (SGPT) levels in Wistar rats induced with fatty liver. This
research employs a post-test-only experimental design with a control group,
involving 18 rats divided into 3 treatment groups (high-fat diet group, control
group, and cherry fruit extract group). The high fat diet group receives high fat
food, the control group receives standard food, and the cherry fruit extract
group receives high fat food along with 100 mg/kg body weight of cherry fruit
extract. SGPT levels are assessed using one-way ANOVA followed by Tukey's
post hoc test. The conclusion of this research indicates that cherry fruit extract
can reduce SGPT levels in rats fed with high fat diet along with the cherry fruit
extract.
Keyword : NAFL, cherry fruit extract
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