CD Skripsi

Sintesis Dua Analog Kalkon Dari Asetilnaftalen Dengan 4-Hidroksibenzaldehid Serta Uji Aktivitasnya Sebagai Antibakteri

---

Two chalcone derivatives have been synthesized from 4-hydroxybenzaldehyde with 1-acetylnaphthalene using KOH 6 N catalyst by aldol condensation using microwave iradiation and 4-hydroxybenzaldehyde with 2-acetylnaphthalene using SOCl2 catalyst using stiring method. Synthesis result have been obtained two compounds, (E)-3-(4-hydroxyphenyl)-1-(naphthalene-1-il)prop-2-en-1-on (CR1) and (E)-3-(4-hydroxyphenyl)-1-(naphthalene-2-il)prop-2-en-1-on(CR2) that have been obtained consecutively were in 68,26 % dan 90,58 % yields. The purity of product have been evaluated by using TLC and boiling point evaluation. The structures of the synthesized compound were confirmed by UV-VIS ,FT-IR, NMR and MS measurements. Evaluation of antibacterial activity were determined by agar diffusion method in concentration of 10 and 30 μg/disk for each evaluation compound. Bacteria that have been used for this evaluation were Staphylococcus aureus and Bacillus subtilis (positive gram bacteria) and Escherichia coli and Salmonella enteritidis (negative gram bacteria). Chalcone compounds have shown different antibacterial activity against each bacterial.
Keywords: agar diffusion, antibacterial evaluation, chalcone

---

Ketersediaan

Informasi Detail

Judul Seri

-

No. Panggil

03 02. 115 (0001)

Penerbit

Pekanbaru : Universitas Riau – FMIPA - Kimia., 2015

Deskripsi Fisik

xii,36 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

-

Klasifikasi

03 02. 115 (0001)

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

-

Subjek

KIMIA

Info Detail Spesifik

-

Pernyataan Tanggungjawab

Dewa

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar