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Pola Sensitivitas Isolat Klinis Bakteri Gram Negatif Multiresisten Obat Terhadap Fosfomisin Dari Beberapa Rumah Sakit Kota Pekanbaru

Over the last few years, there has been a degradation in amount of effective antibiotics, coincide with the lack of new antibiotics relevant for the treatment of Gram negative multi-drug resistant organisms infections. This problem can be overcome by the assessment and re-introduction of old antibiotics such as fosfomycin. Fosfomycin is a bactericidal antibiotics that has a board spectrum. Some studies have found that 90% of the isolates of multi-drug resistant organisms are sensitive to fosfomycin. This study aimed to find out the sensitivity pattern of clinical isolate multi-drug resistant Gram negative bacteria to fosfomycin with descriptive cross sectional method. The sample used in this study is clinical isolates collection of Microbiology Laboratory Faculty of Medicine, University of Riau from Hospitals in Pekanbaru. The result of this study showed sensitivity of E.coli producing ESBL, K.pneumoniae producing ESBL, A.baumanii resistant meropenem, P.aeruginosa resistant meropenem and K.pneumoniae resistant meropenem to fosfomycin are 88%, 95%, 27%, 36% and 70%. Clinical isolates that have the highest sensitivity to fosfomycin is K.pneumoniae producing ESBL and the lowest sensitivity is A. baumanii resistant meropenem. Fosfomycin can be used as alternative therapy for infections caused by Gram-negative Multi-drug resistant organisms.
Keyword : Fosfomycin, Gram-negative, multi-drug resistant organisms

Ketersediaan
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Perpustakaan Universitas Riau 08 01. 118 (0041)
08 01. 118 (0041)
Tersedia
Informasi Detail
Judul Seri
-
No. Panggil
08 01. 118 (0041)
Penerbit
Pekanbaru : Universitas Riau – Fakultas Kedokteran – Pendidikan Kedokteran.,
Deskripsi Fisik
xi, 47 hlm.; ill.; 29 cm
Bahasa
Indonesia
ISBN/ISSN
-
Klasifikasi
08 01. 118 (0041)
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
-
Subjek
PENDIDIKAN KEDOKTERAN
Info Detail Spesifik
-
Pernyataan Tanggungjawab
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Tidak tersedia versi lain

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