CD Skripsi
Profil Penderita Hepatitis B Kronik Yang Mendapat Terapi Antiviral Di RSUD Arifin Achmad Provinsi Riau Periode 2013-2017
Chronic hepatitis B is a global health problem. Hepatitis B virus (HBV) had infected 2 billion of the world’s population, and 257 million of them suffer chronic hepatitis B. There are two classes of antiviral therapy (interferon and nucleos(t)ida analogues) which aim to suppress viral replication and eventally prevent the progression of necroinflamation in the liver. This study aimed to determine the profiles of chronic hepatitis B patients who received antiviral therapy in RSUD Arifin Achmad Riau Province. This is a descriptive study with cross-sectional design analysis medical record data of chronic hepatitis B patients during period 2013-2107 with total sampling method. This research included 31 patients. The average age of patients was 42,94 ± 13,038 years, 67,7% were male, 80,6% were treated with telbivudin. The median value of patient’s HBV DNA levels was 1,69x106 IU/mL and the median value of patient’s ALT levels was 85 IU/L. Transient elastography showed that 48,4% of chronic hepatitis B patients mostly had moderate to severe stage (F2-F4) of liver damage.
Keywords: antiviral therapy, chronic hepatitis B, HBV DNA
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