CD Skripsi

Gambaran Histopatologi Pankreas Tikus Putih (Rattus Norvegicus) Pasca Perlakuan Iskemia-Reperfusi Ginjal

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Ischemic-reperfusion injury is defined by a condition of hypoperfusion in the spesific organ followed by reperfusion (reoxygenation) inducing tissue damage. Tissue damage produces reactive oxygen species (ROS) leading to oxidative stress condition. Oxidative stress mediate the lipid peroxidation reactions, harm the cell and finally facilitate the cell death. The aim of this study was to characterize the histopathology of white rat’s pancreas post renal ischemia-reperfusion. It was an experimental laboratory research with post-test-only control group design including 20 male white rats. Rats were divided into 5 groups, control, treatment 1 (45 minutes ischemia), treatment 2 (45 minutes ischemia followed by 1 hour reperfusion), treatment 3 (45 minutes ischemia followed by 2 hours reperfusion) and treatment 4 (45 minutes ischemia followed by 24 hours reperfusion). We found the histopathological characteristics of white rat’s pancreas in the form of edema and mild vacuolization in treatment group 1. Edema, leukocyte infiltration and mild vacuolization in treatment groups 2 and 3. Edema, leukocyte infiltration and moderate vacuolization in treatment group 4.

Keywords: renal ischemia-reperfusion, pancreas, reactive oxygen species (ROS)

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

08 01. 119 (0085)

Penerbit

Pekanbaru : Universitas Riau – Fakultas Kedokteran – Pendidikan Kedokteran., 2019

Deskripsi Fisik

vi, 71 hlm.; ill.; 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

08 01. 119 (0085)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KEDOKTERAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

DAUS

Versi lain/terkait

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