CD Skripsi

Analisis Ekspresi Gen Reseptor Androgen Dan Profil Pasien Karsinoma Sel Ginjal Tipe Papillary

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Papillary Renal Cell Carcinoma (pRCC) is a malignancy of the renal epithelium with a papillary structure. Previous research suggested a suspected role for steroid receptors in the progression of pRCC. The incidence of pRCC is highest in men and the age range is 60-80 years. This implies that androgen receptors may play a role in the proliferation and progression of pRCC. The purpose of this study is to compare the expression of androgen receptor gene in normal kidney tissue and pRCC tissue and to investigate the possible correlation between these discrepancies and the profile of pRCC patients. Data was extracted from TCGA, GTEx, and The Human Protein Atlas database using cross-sectional analytical research design and total sampling procedure. The results of this investigation demonstrated that the majority of pRCC patients were 58-90 years old, men, white race, and early stage. AR gene expression was significantly higher in pRCC tissue compared to normal kidney tissue (p < 0.001). In conclusion, significantly higher differences in AR gene expression were found in the male group and early stage pRCC, but not significantly in the age and race groups.
Keywords: AR gene expression, pRCC, pRCC patient profile.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2008111247

Penerbit

Pekanbaru : Universitas Riau - FK – Pendidikan Dokter., 2023

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2008111247

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

PENDIDIKAN DOKTER

Info Detail Spesifik

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Pernyataan Tanggungjawab

Jaka

Versi lain/terkait

Lampiran Berkas

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