CD Skripsi

Hubungan Ekspresi Gen Androgen Receptor (AR) Dengan Prognosis Pasien Papillary Renal Cell Carcinoma

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Papillary Renal Cell Carcinoma (pRCC) is a subtype of RCC with the second highest incidence after ccRCC. pRCC originates from the renal tubular epithelium and has a papillar-shaped structure, well-defined, with basophilic cytoplasm. Several studies have found that Androgen Receptor (AR) gene expression is associated with cancer progression. This study aims to determine the role of AR gene expression in the prognosis of pRCC patients. This study took 200 samples from https://xenabrowser.net with an observational analytic research design and retrospective cohort approach. From the results of this study, Hastil showed that there was no significant relationship between clinical profile and AR gene expression. There was also no significant relationship between overall survival (OS) and progression-free survival (PFS) with clinical profiles such as age and gender. However, the relationship between OS and PFS with stage was significant. There was no significant relationship between AR gene expression and OS and PFS. It can be concluded that AR gene expression has no relationship with AR gene expression and cannot be used as an independent biomarker for the prognosis of pRCC patients.


Keywords: Androgen Receptor, Papillary Renal Cell Carcinoma, prognosis, survival.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2008113752

Penerbit

Pekanbaru : Universitas Riau - FK – Pendidikan Dokter., 2024

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2008113752

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

PENDIDIKAN DOKTER

Info Detail Spesifik

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Pernyataan Tanggungjawab

Jaka

Versi lain/terkait

Lampiran Berkas

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