CD Skripsi

Pengaruh Ekstrak Etanol Daun Seri (Muntingia Calabura) Terhadap Kadar Glukosa Darah Tikus Wistar Yang Diinduksi Diet Tinggi Lemak

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An increase in blood glucose levels is a common condition resulting from insulin resistance or impaired insulin secretion. The leaves of Muntingia calabura, contain phytochemical compounds such as flavonoids, terpenoids, tannins, and saponins, which have anti-inflammatory properties and are assumed to have potential in lowering blood glucose levels due to insulin resistance. This study aims to analyze the effect of ethanol extract from Jamaican cherry leaves on hyperglycemic rats induced by a high-fat diet. This experimental study used a post-test-only design with 16 male Wistar rats divided into four groups. The standard diet group was given only standard feed and distilled water, while the negative control, positive control, and treatment groups were all induced with a high-fat diet (50%). The positive control group was given Pioglitazone at 3.1 mg/kg body weight, while the treatment group received Jamaican cherry leaf extract at 100 mg/kg body weight. The rats were terminated in the eighth week, and blood glucose levels were measured using the enzymatic colorimetric GOD-POD method. The results showed that the average blood glucose levels in the standard diet, negative control, positive control, and treatment groups were 116.67 ± 14.38, 164.67 ± 15.53, 189.45 ± 22.68, and 226.21 ± 15.83, respectively. Statistical tests indicated a significant difference between the Jamaican cherry leaf extract treatment group and the negative control group (p < 0.05). It can be concluded that the ethanol extract of Jamaican cherry leaves has not been able prevent an increase in blood glucose levels caused by a high-fat diet.

Keyword : blood glucose, high-fat diet, Muntingia calabura

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2108124944

Penerbit

Pekanbaru : Universitas Riau FK Pendidikan Dokter., 2024

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2108124944

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

PENDIDIKAN DOKTER

Info Detail Spesifik

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Pernyataan Tanggungjawab

Jaka

Versi lain/terkait

Lampiran Berkas

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