Streptococcus mutans (S. mutans) is a bacterium that has surface glucosyltransferase (GTFs) enzymes that play a role in the attachment process and the virulence of bacteria on the tooth surface. Various Gtfs enzymes can be found in Streptococcus mutans, one of which is the gtfD gene which acts as a precursor in cellular adhesion of dental plaque that can cause dental caries. Objective: Thi…