Atherosclerosis is arterial wall’s disease initiated by lipid retention, oxidation, and modification, provoking chronic inflamation ultimately causing stenosis and thrombosis. Alpha-lipoic acid (ALA) is naturally found in mitochondria that exerts anti-oxidant and anti-inflamatory effect associated with abnormal oxidative stress and inflamation on diabetes melitus (DM) . This study investigate…
Hypertension is risk factor cause of the chronic disease such as kidney failure, coronary heart disease, and stroke. The increasing incidence and prevalence of hypertension depends on several factors such as age, gender, level of knowledge, family history, and the level of adherence medication. This research has aims to analyze the relationship between the level of adherence medication with blo…
Beta cell damage due to inflamation process can cause hyperglycemia. It can be due to increase of free radical and the decrease of endogen antioxidant that might lead to oxidative stress. Alpha lipoic acid (ALA) has several antioxidant effect such as binding ROS (radical oxygen species), chelating metal, regenerating endogen antioxidant and exacerbating cell damage. The aim of this research wa…
Isoflavones which have been known having anti diabetic effect. Fermentation process of soybean can lead to formation aglycan isoflavones which have higher bioavailability than unfermented-soybean. The aim of this research was to know the effect of soybean and tempeh (fermented-soybean) administration to oral glucose tolerance test (OGTT) in diabetic rats. This research was experimental by using…
Hypercholesterolemia is complication in type 2 diabetes. Alpha lipoic acid (ALA) can reduce total cholesterol by modulating cholesterol synthesis pathway and reduced cholesterol biosynthesis genes expression. The goal of this research was to investigate prohibition of hypercholesterolemia in type 2 diabetes rat by ALA. Fifteen adult male wistar rats (2-3 months 200-250 g body weight) were segre…
Street sweepers are thought to be susceptible of changes in lung function due to frequent exposure of air pollution and other influenced factors. This study aim was to assess the lung physiology of the street sweepers staff of Pekanbaru City Sanitation Department. The study design was descriptive cross sectional. The study included 61 street sweepers of Pekanbaru City Sanitation Department take…
Pediculosis capitis is categorized as a neglected disease and it’s still become a problem for public health. Pediculus humanus capitis infestation is easily transmitted directly between individuals or personal objects used together. Pediculosis capitis has various risk factors that can increase the occurrence of Pediculus humanus capitis infestation. The disease affects all ages especially ju…
Diabetes mellitus type 2 is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. One of the most complications of diabetes is diabetic neuropathy. The aim of this study is to identify patients at risk for diabetic neuropathy with monofilament examination in internist polyclinic Arifin Achmad General Hospital from May t…
Paraquat is a herbicide that is often used in Indonesia and other developing countries. Paraquat is toxic to humans with the result that using paraquat inappropriately to the rules can cause poisoning in humans. Paraquat damages organs including the lung, causing death because of breathing failure. The purpose of this study was to determine the effects of paraquat on lung fibosis histopathology…
Isoflavone contents especially genistein, daidzein, and glycetin in soybean have been known as antidiabetic agents. Fermentation process in soybean can decrease 65% phytat acid amount and initiate the formation of aglycone isoflavone which can increase mineral bioavailability. The aim of this research is to analyze soybean and tempeh (soybean fermentation product) administration effect to the d…
The air quality crisis in cities is mainly due to motor vehicle emissions. Increased air pollution will have serious negative effects on health, especially lung health. The purpose of this study is to overview the lung functions on highway traffic policemen in polresta pekanbaru. The type of this research is descriptive cross sectional type. The sample used is the traffic policemen who is on du…
Obstrurctive uropathy is an obstructive condition of urinary due to structural changes and function. Prolonged obstruction of urinary tract may damage renal parencyhm and disrupt its function. Removing the urinary tract obstruction can improve renal function by 30 to 80%. This study purpose was to present profile of patient with obstructive uropathy that treated by removing renal stone or urete…
Academic achievement is influenced by internal and external factors. One of the internal factor is eyes health. Refractive error can be a potential disruption on student’s academic achievement. This study aimed to determine the effect of refractive error on academic achievement of students from SDN 106 Pekanbaru. This is analytical observational study with cross-sectional approach. The sampli…
Soybean isoflavone has insulinotropic effect, apart from its potent antioxidant effect. Fermentation process of soybean in the making of tempeh increases isoflavone bioavailability by changing the type of isoflavone into aglikan, and also by decreasing antinutrition and fitat acid level. The objective of this study was to compare serum triglyceride level from diabetic rat after administration o…
Oxidative stress increase in type 2 diabetes mellitus (DM). This might cause complications, one of them is atherosclerosis. Alpha lipoic acid (ALA) is antioxidant which could have potential preventing atherosclerosis. This research investigated effects of ALA on atherosclerosis lesion score in rats-induced type 2 DM. Fifteen male Wistar rats (± 2 - 3 months old, 200-250 gBW) were devided into …
Urinary tract infection (UTI) is an infection due to the proliferation of microorganisms in the urinary tract. These infections can be categorized as symptomatic or asymptomatic. Generally Urinary Tract Infection is caused by Gram negative germs such as Escherichia coli which is the most cause of UTI is 70 - 90%. Other causal bacteria are Klebsiella pneumonia and Pseudomonas aeruginosa. In pati…
ESBL-producing Klebsiella pneumoniae is an opportunistic pathogen that has emerged as nosocomial infection. The objective of this study was to analyze risk factors of ESB-producing Klebsiella pneumoniae in Arifin Achmad General Hospital, Riau Province. The design of this study was analytic with case-control study approach (50 case groups and 50 control groups). Data on inpatient culture results…
Urethral stricture is one of complications in urology. Urethral stricture still became a health issue because the increasing number of incidence and cause of increasing in morbidity. The aim of this research is to know the of management on urethral stricture based on age, gender, clinical symptom, etiology, examination of radiology, classification, management and complication. This research use…
Obesity is a concerning problem all over the world, because of its prevalence that has continue to rise in adults, adolescents and children. The purpose of this study was to reveal the effect of health education on the awareness and knowledge of adolescents in management of obesity. This research has been carried out using quasi-experimental design with obese adolescents as subjects. The behavi…
Heart Failure (HF) become a serious health problem nowadays. Hemodynamic relation between heart and renal called Cardiorenal connector is responsible for worsening renal function. HF that causes worsening of renal function belongs to the category of Cardiorenal Syndrome (CRS). Worsening renal function can be seen from creatinine serum levels, if creatinine serum levels increase, thus renal func…