hubungan tingkat metilasi dna dan ekspresi Mrna gen h19 pada pasien oligozoos…

Oligozoospermia, occurs in 34.14% of male infertility cases, define as sperm concentration counted less than 15 million sperm/mL/ejaculation. One of the factor that affects sperm concentration is epigenetic factors, including DNA methylation. We hypotized that sperm concentration is affected by the DNA methylation of H19 gene, a significant gene in fetal growth and development, especially in th…