Oil palm production decreased due to plant disrupting organisms (PDO) such as horned beetle pests (Oryctes rhinoceros Linn.). Control of O. rhinoceros pests generally uses synthetic insecticides. Alternative control can use vegetable insecticides, one of which is japanese papaya leaves (Cnidoscolus aconitifolius I. M. Johnst). C. aconitifolius contain secondary metabolite compounds such as cya…