CD Skripsi

Isolasi Dan Uji Toksisitas Senyawa Metabolit Sekunder Ekstrak N-Heksana Dari Tumbuhan Putri Malu (Mimosa Pudica Linn)

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The Mimosa pudica is a South American and Central American plant that is
commonly found in Indonesia. M. pudica is used as a herbal medicine in
Indonesia to treat a variety of diseases. However, the toxicity of this plant has not
been thoroughly investigated. Therefore, it is necessary to isolate secondary
metabolites and analyzed for their toxicity, as well as extracts. Isolation was
accomplished through the maceration method with methanol and partitioning with
n-hexane, dichloromethane, and ethyl acetate. The crude n-hexane extract was
separated using Vacum Liquid Chromatography (VLC) and resulting 24 fractions.
Fraction no 4C and 10 were found to contain crystals and recrystalisation was
performed to obtain white crystal, and they were coded as 20-06-A-F4 and 20-06-
A-F10. The crystals were observed to have melting point ranges 144-146 oC and
82-84 oC, respectively. FT-IR spectrophotometry analysis was used to analyze 20-
06-A-F4 and 20-06-A-F10. The results revealed alcohol absorption band (-OH) at
3.298 cm-1, C-H aliphatic absorption band at 2.937 cm-1, absorption band (C=C) at
1.654 cm-1, and absorption band (–CH2) at 1,458 cm-1 in 20-06-A-F4.
Furthermore, The FT-IR spectrophotometry analysis of 20-06-A-F10 revealed a (-
OH) absorption band at 3,308 cm-1, a (C-H aliphatic) absorption band at 2,849-
2,956 cm-1, and a (C=O) absorption band at 1,730 cm-1. 20-06-A-F4 and 20-06-AF10
were assigned as β-sitosterol and fatty acid methyl esters. The Brine Shirmp
Lethality Test (BSLT) results revealed that the crude extract of n-hexane and its
fraction were not toxic.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

03 02. 121 (0036)

Penerbit

Pekanbaru : Universitas Riau – FMIPA – Kimia., 2021

Deskripsi Fisik

xii, 27 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

03 02. 121 (0036)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

ELFITRA

Versi lain/terkait

Lampiran Berkas

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