Abstract Indragiri River is one of the largest rivers in Riau Province. This study aims to assess the water quality of the Indragiri River based on the Epilithic Periphyton Biodiversity Index. The research location is in Lubuk Terentang Village, Gunung Toar District, Kuantan Singingi Regency, Riau Province. The time chosen for the research is in February 2021. The samples were taken from 3…