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Deteksi Β-Globin Dan Hpv Dari Jaringan Serviks Pada Pasien Kanker Serviks

Cervical cancer is cancer that occurs in the uterine cervix, an area which is the
entrance to the uterus that located between the uterus and the vagina. The main
risk factor driving the development of cervical cancer is persistent infection with
hrHPV. Screening for cervical cancer is necessary to prevent cervical cancer.
Among several cervical cancer screening techniques, the HPV DNA identification
test is relatively simpler than the cytological test. The presence of sufficient DNA
to allow HPV testing was assessed by detection of the b -globin gene in the sample.
This study is a descriptive study to see the quality of detection of b -globin and HPV
genes in cervical tissue of cervical cancer patients at the Arifin Achmad Hospital
and was carried out at the Integrated Biomedical Laboratory, Faculty of Medicine,
Riau University from October 2021 – February 2022. Based on the results of this
study, it can be taken the conclusion is that the optimal method of extracting DNA
from b-globin and HPV in cervical tissue of cervical cancer patients at RSUD Arifin
Achmad is the automatic method with the torax kit and the optimal PCR method is
the PCR method with multiplex PCR. From a total of 23 cervical tissue samples
from cervical cancer patients at the Arifin Achmad Hospital, the percentage of
cervical tissue samples that were positive for b-globin was 100%, this indicates that
the sample is a human sample while the percentage of cervical tissue samples that
are positive for HPV is 65,22 % and the sample with negative HPV was 34.78 % .
Keywords: Cervical cancer, HPV, b-globin.

Ketersediaan
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Perpustakaan Universitas Riau 08 01.122 (0025)
08 01.122 (0025)
Tersedia
Informasi Detail
Judul Seri
-
No. Panggil
08 01.122 (0025)
Penerbit
Pekanbaru : Universitas Riau – Kedokteran – Pendidikan Dokter.,
Deskripsi Fisik
xv,43 hlm.: ill.: 29 cm
Bahasa
Indonesia
ISBN/ISSN
-
Klasifikasi
08 01.122 (0025)
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
-
Subjek
PENDIDIKAN DOKTER
Info Detail Spesifik
-
Pernyataan Tanggungjawab
Versi lain/terkait

Tidak tersedia versi lain

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