CD Skripsi
Polimorfisme Gen Reseptor Vitamin D (Rvd) Taqi Pada Dewasa Muda Dengan Obesitas Sentral
ABSTRACT
POLYMORPHISM GENE VITAMIN D RESEPTOR (VDR) TaqI IN YOUNG ADULTS WITH CENTRAL OBESITY
By
Rakha Muhammad Farras
Central obesity is the accumulation of fat in the abdominal region of the body caused by excessive amounts of fat. Obesity is associated with vitamin D deficiency. Vitamin D through the receptor vitamin D (RVD) encoded by the RVD gene has several polymorphisms that have several alleles that are associated with obesity. The RVD TaqI gene allele is associated with obesity. The purpose of this study was to determine the description of vitamin D receptor (RVD) TaqI gene polymorphism in young adults with central obesity. The type of research used is descriptive to see the description of the frequency distribution of central obesity, genotypes, and alleles in the RVD TaqI gene polymorphism in young adults. RVD TaqI gene polymorphism examination was carried out at the Integrated Biomedical Laboratory, Faculty of Medicine, Riau University by Amplification Refractory Mutation System-Polymerase Chain Reaction (ARMS-PCR) examination. In this study, there are 44 respondens. Female had the highest frequency (59.1%). The highest age was 19 years old (36.3%). The most common genotype of TaqI RVD gene polymorphism in respondents was TT 38 people (86,4%) and the most common allele in respondents was the T 79 allele (89,8%).
Keywords: Central obesity, young adults, TaqI, RVD gene polymorphism.
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