CD Skripsi

Deteksi Resistensi Larva Aedes Aegypti Berdasarkan Aktivitas Enzim Monooksigenase Di Kelurahan Tangkerang Barat Kecamatan Marpoyan Damai Kota Pekanbaru

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ABSTRACT
DETECTION OF Aedes aegypti LARVAE RESISTANCE
BASED ON MONOOXYGENASE ENZYME ACTIVITY IN TANGKERANG BARAT VILLAGE MARPOYAN DAMAI DISTRICT
PEKANBARU
By:
Muhammad Randy Kurniadi
Aedes aegypti is a vector that transmits the dengue virus causing Dengue Hemorrhagic Fever (DHF). DHF is transmitted through the bite of a female Aedes aegypti containing dengue virus. One way to control Aedes aegypti population is chemical control using insecticides. The long term use of insecticides without including rotation can cause Aedes aegypti resistance. Resistance of Aedes aegypti can be tested biochemically to detect enzyme activity in vectors. Monooxygenase is one of the detoxification enzymes related to pyrethroid insecticides and the increase in this enzyme occurs because pyrethroids are widely used as a household insecticide. This study aimed to determine the resistance status of Aedes aegypti larvae based on the activity of the monooxygenase enzyme in Tangkerang Barat Village, Marpoyan Damai District. This was a descriptive research with a cross-sectional and laboratory design which was carried out from October 2022-January 2023. The samples came from 100 houses in West Tangkerang Village with a total of 150 Aedes aegypti larvae used. The selection of the sampling houses used the purposive sampling method and the larvae were collected using the consecutive sampling technique at 100 houses. Determination of the species of Aedes aegypti larvae used the single larva method and the larvae were selected using the simple random sampling method. Biochemical resistance test was carried out on Aedes aegypti larvae to see monooxygenase enzyme activity qualitatively by looking at color changes and semi-quantitatively using an ELISA reader. Based on the results of resistance tests with qualitative and semi-quantitative assessments, it was shown that most of the Aedes aegypti larvae in Tangkerang Barat Village were still susceptible to pyrethroid insecticides. This study shows that the pyrethroid insecticides can still be used in controlling Aedes aegypti mosquitoes in the Tangkerang Barat Village, Marpoyan Damai District.
Keywords: Aedes aegypti, insecticide, monooxygenase, resistance

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

1908155304

Penerbit

Pekanbaru : Universitas Riau – Fakultas Kedokteran – Pendidikan Kedokteran., 2023

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

1908155304

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KEDOKTERAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

TIAR

Versi lain/terkait

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