CD Skripsi
Aktivitas Antimikroba Ekstrak Metanol Daun Mangifera Sumatrana Terhadap Mikroba Patogen Kulit
Mango (Mangifera spp.) is a fruit bearing plant belonging to the Anacardiaceae family. Mangifera sumatrana is a semi wild or semi cultivated type of mango. M. sumatrana leaves contain high levels of antioxidant, phenolic and flavonoid compounds and have potential as an antibacterial candidate. This study aims to test the antimicrobial activity of methanol extract of Mangifera sumatrana leaves against skin pathogenic microbes. This research was carried out using the maceration extraction method using 70% methanol solvent and antimicrobial activity testing using the disc diffusion method. The results of the research showed that Mangifera sumatrana leaf extract against the bacteria Staphylococcus aureus ATCC 6538 and Propionibacterium acnes ATCC 6916 at each concentration variation formed an inhibitory zone, the largest inhibitory zone was produced at a concentration of 80%. The average diameter of the inhibition zone in S. aureus is
14.42 mm which is classified as Intermediate, and in P. acnes it is 15.55 mm which is classified as Intermediate. S. aureus used the positive control chloramphenicol 30 μg, the resulting zone was 26.22 mm, and P. acnes used the positive control erythromycin 15 μg, the resulting zone was 25.90 mm. However, no inhibition zone was formed at each concentration variation for the Candida albicans ATCC 10231.
C. albicans used a positive control of 25 μg fluconazole, the resulting zone was
31.39 mm.
Key finding: Antimicrobial activity, Disc diffusion, Mangifera sumatrana, Methanol extract, Skin Pathogens.
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