CD Skripsi

Distribusi tipe kanker endometrium berdasarkan ekspresi reseptor estrogen

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Endometrial cancer is a malignant tumor of epithelial cells in the endometrium. The etiology of cancer is related to the unopposed estrogen theory so that atypical endometrial hyperplasia occurs and causes malignancy. The endometrial epithelium expresses estrogen receptors that bind to estrogen. The expression of estrogen receptors is used as a reference to determine the type of endometrial cancer and hormonal therapy planning. This study used a descriptive study with cross-sectional approach to see distribution of endometrial cancer types based on results of estrogen receptor staining. The population in this study were all post-hysterectomy endometrial cancer patients at the Arifin Achmad Hospital, Riau Province in period 2019-2024 with sample of 44 patients. In this study, immunohistochemical examination was performed using paraffin blocks of endometrial cancer patients stained with estrogen receptor antibodies and assessed using Allred Score criteria. The analysis was carried out univariately. There were 44 patients with type I endometrial cancer divided into 35 patients including positive estrogen receptors (79.5%) and 9 patients including negative estrogen receptors (20.5%). The most common risk factors for positive estrogen receptor expression were age ≥50 years, multiparity, obesity, no hypertension, and no diabetes mellitus. The most common risk factors for negative estrogen receptor expression were age

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2108113797

Penerbit

Pekanbaru. : Universitas Riau – F.KEDOKTERAN – KEDOKTERAN., 2025

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2108113797

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KEDOKTERAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

Rahmat

Versi lain/terkait

Lampiran Berkas

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