CD Skripsi
Hubungan Derajat Klinis Dengan Kadar Feritin Penyandang Thalassemia β Di RSUD ARIFIN ACHMAD
Thalassemia is a genetic disorder which there is trouble with the synthesis of hemoglobin that causes a decreased of synthesis of α or β chain, If the abnormality is β chain, it called β thalassemia. People with thalassemia need transfusion of red blood in rest of their life to maintain sufficient hemoglobin level, but the result is increased level of iron overload in body which can cause complication. The aim of this research was to see the description and the correlation between clinical severity with ferritin level of β thalassemia at Arifin Achmad Hospital in Riau province. The method used was analytic with cross sectional approach. Disease severity calculated by Thailand score whereas ferritin level scored by laboratory test. Of 59 people with β thalassemia there were as many as 49 people (83.1%) with moderate disease severity and 10 people (16.9%) with severe disease severity, whereas ferritin levels 2500 ng/ml as many as 39 people (66.1%). After analysis, there was not correlation between disease severity with ferritin level (p>0.05). The conclusion of this study, the highest data were thalassemia with moderate disease severity and ferritin level at >2500 ng/ml, also there was not correlation between disease severity with ferritin level.
Keyword: β Thalassemia, Disease Severity, Ferritin level.
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