CD Skripsi

Sintesis, Uji Toksisitas Dan Antioksidan Senyawa 1-(Naftalen-1-Ilmetilen)-2-Fenilhidrazin

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Hydrazone is an organic compound that has a variety of biological activities such as antioxidant and anticancer. The active group of hydrazone compound the azomethin group (-NHN=CH-) makes this compound as an important compound in the development of new drugs. Hence, in this study, the synthesis of hydrazone 1-(naphthalene-1-ylmetilen)-2-phenylhydrazine (IFA-ND1) was obtained from the condensation reaction between 1-naphthalene and phenylhydrazine catalyzed by acetic acid. This compound was synthesized by microwave irradiation method at 180 Watt. The purity of the compound is determined by using TLC, melting point and HPLC analysis. The structure of the synthesized compound was confirmed by UV, FTIR, NMR, and HRMS spectroscopic analyzes. The bioactivity of the IFA-ND1 compound was evaluated with its toxicity properties by BSLT method while antioxidant activity was tested by DPPH method. The results of this research were IFA-ND1 compound successfully synthesized with 72.35% yield, toxicity with LC50 = 1.455 μg/mL and has antioxidant activity with IC50 = 28.9051 μg/mL. This suggests that the IFA-ND1 compound is a potential compound with toxic properties and as antioxidant.
Keywords : antioxidant, azomethine, hydrazone, toxicity

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

03 02. 120 (0039)

Penerbit

Pekanbaru : Universitas Riau – FMIPA – Kimia., 2020

Deskripsi Fisik

xv, 35 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

03 02. 120 (0039)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

ELFITRA

Versi lain/terkait

Lampiran Berkas

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