CD Skripsi

Sintesis, Uji Toksisitas Dan Antioksidan Senyawa (1-(Naftalen-2-Il)Etiliden)Hidrazin

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SUMMARY
Hydrazone is an organic compound that has a basic structure (R1R2C=N-NR3R4). Azomethine (-NHN=CH) is the active group of the hydrazone compound, which makes this compound has a variety biological activities. In this research, the synthesis of the hydrazone compound (1-(naphtalene-2-il)ethyliden)hydrazine (IHK-AN2) obtained from the condensation reaction between 2-acetylnaphtalene and hydrazine hydrate catalyzed by acetic acid. The compound was synthesized using microwave irradiation method with 180 watt. The purity of the compound was determined by TLC, melting point measurement and HPLC analysis. The compound was anakyzed by spectroscopic analysis such as UV, FTIR, HRMS and NMR. Synthesis of hydrazone in this research was concluded with a yield 85,86%. The toxicity of the IHK-AN2 compound was evaluated by BSLT method and antioxidant activity was tested by DPPH method. LC50 value of the compound was >1000 μg/mL and IC50 value was 644,73 μg/mL. From the data above was concluded that the IHK-AN2 compound was not toxic and inactive as antioxidant.
Keywords: antioxidant, hydrazone, toxicity

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

03 02. 121 (0021)

Penerbit

Pekanbaru : Universitas Riau – FMIPA – Kimia., 2021

Deskripsi Fisik

ix,112 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

03 02. 121 (0021)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

ELFITRA

Versi lain/terkait

Lampiran Berkas

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