CD Skripsi

Sintesis Dan Uji Toksisitas Senyawa N’1,N’3-Bis((E,E)-2-Bromobenziliden)Malonohidrazid

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Hydrazone which is a compound with the group ‒CH=N‒NH‒. Hydrazone
containing azomethin -NHN=CH- can be synthesized by heating at a certain
temperature by substituting hydrazine/hydrazide with an aldehyde and has various
bioactivities such as anti-cancer, anti-inflammatory, and anti-bacterial. For further
development in this research, the synthesis of the compound
N'1,N'3-bis-((E,E)-2-bromobenzyliden)malonohydrazide was carried out by reacted
malonohydrazide with 2-bromobenzaldehyde added glacial acetic acid catalyst to
accelerate the formation reaction through a condensation reaction used heating
method (reflux) at temperature 50-60°C and stirring. The yield of the purity of the
compound was determined by using the TLC, melting point and HPLC analysis. The
purified compounds were identified using spectroscopic analysis of UV, FTIR,
HRMS, 1H-NMR, 13C-NMR and HMBC. Toxicity test was determined by BSLT
method used shrimp larvae (Artemia salina Leach). Based on the results of research
that has been carried out, the DB-2Br compound has been successfully synthesized
with a yield of 90%, and is toxic with a value of LC50 = 2.8 μg/mL.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

03 02. 121 (0064)

Penerbit

Pekanbaru : Universitas Riau – FMIPA – Kimia., 2021

Deskripsi Fisik

xi, 29 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

03 02. 121 (0064)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

ELFITRA

Versi lain/terkait

Lampiran Berkas

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