CD Skripsi

Deteksi Gen Gtf-D Streptococcus Mutans Pada Karies Gigi Penderita Diabetes Melitus Di Rsud Arifin Achmad Provinsi Riau

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Streptococcus mutans (S. mutans) is a bacterium that has
surface glucosyltransferase (GTFs) enzymes that play a role in the attachment
process and the virulence of bacteria on the tooth surface. Various Gtfs enzymes
can be found in Streptococcus mutans, one of which is the gtfD gene which acts as
a precursor in cellular adhesion of dental plaque that can cause dental caries.
Objective: This study aims to identify the gtfD gene of S. Mutans in dental caries in
DM sufferer at Arifin Achmad Regional Public Hospital, Riau Province. Methods:
This study used a prospective descriptive design with consecutive sampling.
Research samples were taken from dental caries tissue scrapings, isolated,
cultured, and identified in the Microbiology and Central Laboratory of the Faculty
of Medicine Universitas Riau. Identification of S. mutans and GtfD cariogenic
genes using the Polymerase Chain Reaction (PCR) method. The data was displayed
in the form of a frequency distribution table and expressed as a percentage. Results:
The characteristics of DM sufferers with the most caries were 56-65 years old
(56.66%) and 46-55 years old (26.66%), female (56.67%) and male (43.33). %),
the housewives (IRT) (40%) and PNS/TNI/POLRI/Retirees (33.33%), senior high
school education (40%) and elementary school (26.67%), uncontrolled DM status
(80%) and controlled (20%); ten isolates of S. mutans bacteria (33,33%), while the
gtfD gene obtained 4 isolates each (40%). Conclusion: The cariogenic gene was
identified as the gtfD gene in 40% of S. mutans isolates from dental caries patients.
Keywords : Streptococcus mutans, Glukosiltransferase surface, gtfD

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

08 01.122 (0011)

Penerbit

Pekanbaru : Universitas Riau – Kedokteran – Pendidikan Dokter., 2022

Deskripsi Fisik

xvi, 63 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

08 01.122 (0011)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

PENDIDIKAN DOKTER

Info Detail Spesifik

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Pernyataan Tanggungjawab

ELFITRA

Versi lain/terkait

Lampiran Berkas

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