Pyrazoline is a five-ring heterocyclic compound which has two nitrogen atoms close together in the ring and has only one endocyclic double bond. The aim of this study was to synthesize the compound 5- (4-fluorophenyl) -3- (2- hydroxy naphthalene-2-yl)-1-phenyl-4.5-dihydro-1H -pyrazole (PF-NH2-4F). The method used in the synthesis of pyrazoline is the cyclization method with a closed vessel …
Palm oil mill effluent (POME) is a typical organic waste that contains oil and gerease, high values of chemical oxygen demand (COD), total dissolved solid (TDS) and total suspended solid (TSS), thus it is highly polluting. The oil extraction from fresh fruit bunch (FFB) requires a huge amount of water, giving a rise to volumoneous wastewater, which is called as palm oil mill effluent (POME…
Hydrazone is a substitution product of stable imine type which has a basic structure (R1-HC=N-NH-R2). The izometine (-HC=N-NH-) group in hydrazones plays a role in their biological activity for the design and development of drugs. In this study, the synthesis of the compound synthesized N'1,N'3-bis ((E,E)-3-bromobenzilydene)malonohydrazide (DB-3Br) was from the condensation reaction betwee…
Hydrazone is a class of organic compound with the structure R1R2C=NNH2. Hydrazone has an azomethine group (-NHN=CH-), which is an aldehyde and ketone derivative, in which the oxygen atom is replaced by an =NNH2 group. The purpose of this study was to synthesize the compound N'1,N'3-bis ((E,E)-4-bromobenziliden)malonohydrazid and to determine the toxicity of the compound using the BSLT meth…
Hydrazone is a versatile of organic compounds with the structure R1C=N-NHR2. Hydrazones containing an azomethine -NHN=CH- group which is known to possess diverse biological activities such as anticancer, analgesic, antibacterial, anticonvulsant, anti-inflammatory, and antimalarial. The addition of fluoro substituents to the aromatic ring has been shown to improve the pharmacological proper…
The hyperpigmentation caused by melanin production excessive on the skin. So the prevention of hyperpigmentation can be done through the use of a cream containing an inhibitor of tyrosinase. One of the compounds that have activity as inhibitors of the enzyme tyrosinase is pirazolin and pirazol. Pyrazoline and pyrazole are heterocyclic compounds containing two nitrogen atoms, that have vari…
A coffee tree parasite is one of the Loranthaceae family which is distibuted in Indonesia. This plant is widely used as a traditional medicine by various tribes. In previous studies it was reported that several species of this genus have antimalarial, antioxidant, antibacterial and anti-inflammatory properties. This study aims to determine the content of secondary metabolites and determine …
Pineapple is a plant that grows in the tropics and subtropics with the scientific name Ananas comosus. L with several active components, one of them is the bromelain enzyme. The aim of this study was to isolate secondary metabolites of n-hexane extract from pineapple weevil and to test the antimicrobial activity of isolated n-hexane extract and its pure compounds. This research by maceratio…
Aspergillus sp. LBKURCC304 is one of the isolates from the Enzyme, Fermentation, and Biomolecular Research Laboratory of the Faculty of Mathematics and Natural Sciences, Riau University, which semi-quantitatively and quantitatively was known to be able to produce amylase enzyme using starch (KGaA) as a carbon source. Carbon has been thought to greatly effect metabolism, therefore in this s…
A coffee tree parasite (Loranthus ferrugineus) is a type of parasitic plant that is widely used as a medicinal plant. This study aimed to isolate and characterize the pure compound obtained from the n-hexane extract of the its stem and also to perform antioxidant tests on the n-hexane extract. Isolation process was carried out by the maceration method in using n-hexane as solvents, repectiv…
Pyrrosia longifolia is a fern species in the Polypodiaceae family. This species is frequently found attached to old trees, usually on branches or nagging branches. The goal of this study was to isolate secondary metabolites of P. longifolia and analyze their toxicity using the Brine Shrimp Letalithy Test (BSLT). This species was extracted using the maceration method with methanol and fracti…
Pyrazoline is a five ring heterocyclic compounds that cointains two nitrogen atoms in a close position with one double bond in the ring which is known to have various bioactivities such as an anti-oxidant, anti-cancer, anti-microbial, and anti-bacterial. The pyrazoline derivative 5-(4-fluorophenyl)-3-(1-hydroxynaphthalene-2-yl)-1- phenyl-4,5-dihydro-1H-pyrazole (PF-NH1-4F) was synthesized b…
Pyrazoline is a secondary metabolic compound with five circular heterocyclic structures that has three carbon atoms and two nitrogen atoms position close to each other. Pyrazoline has high toxicity and possess various bioactivities such as antitumor and anticancer agent. Pyrazoline (5-(4-bromophenyl)-3-(1- hydroxynaphthalene-2-yl)-1-phenyl-4,5-dihydro-1H-pyrazole has successfully synthesiz…
Coleus hybridus better known as "green iler or green miana" is one of the traditional plants from the Lamiaceae family with various varieties of leaves that used as medicines. This study aims to isolate secondary metabolites and test the inhibition of α-glucosidase activity of green miana. Isolation of compounds was carried out by maceration method using methanol as solvent. The methanol …
Peperomia pellucida or sirih Cina (also called suruhan, tumpang air, sasaladahan) is a herbal plant that has many benefits. It can be found in damp places such as on the edge of ditches, between rocks, wall gaps, and in the yard. This plant has the potential to produce secondary metabolites that might have antidiabetic activity. The aim of this study was to test the activity of the ethyl ac…
Miana (C. hybridus) is an ornamental plant that is widely used as a medicinal plant. This study aimed to isolate secondary metabolites and test α-glucosidase inhibition from these plants. Isolation was carried out by maceration method with methanol and then partitioned with n-hexane solvent to obtain a thick n-hexane extract. Extracts were separated by vacuum liquid chromatography (VLC) an…
Peperomia pellucida is one of species belongs to Piperaceae family which is widely distributed in Indonesia. This plant commonly is used as a traditional medicine by various tribes in Indonesia. Several species of this genus are reported have antidiabetic, antioxidant, antibacterial, and antiinflammatory. This investigation was intended to isolate P. pellucida secondary metabolites from n-…
Water pollution by synthetic dyes has been major environmental concern due to the stability and toxic nature of most synthetic dyes. Thus, it is urgent to find an effective method to solve this problem. Manganese oxides and modified counterpart with tunnel and layered structure have been proposed as heterogeneous Fenton catalyst for the degradation of dyes. In this study, the Ag-MnO2 has be…
Jackfruit peel waste from the production of jackfruit chips in Rimbo Panjang, Kampar, Riau is still wasted and has not been used optimally. From several studies it is known that jackfruit peel waste can be used as an adsorbent. To increase the adsorption ability, an activation process was carried out with NaOH and continued with modification using Ca-alginate. This study aims to determine …
Oil from palm oil processing into crude palm oil generally still contains impurities, so it is necessary to carry out a physical purification process which includes pre-treatment and deodorization processes consisting of degumming and bleaching processes to remove gum and other impurity components. The purpose of this study was to determine the ratio of phosphoric acid in the degumming pro…