CD Skripsi

Sintesis Dan Karakterisasi Senyawa Kalkon (E)-1-(4-(4-Bromobutoksi)Fenil)-3-(3-Metoksifenil) Prop-2-En-1-On

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Chalcone is one of secondary metabolites that has been reported to possess biological activities such as antimicrobial, antitumor, antioxidant, anti-inflammatory, antimalarial, and anticancer. Chalcone can be used as an intermediate for synthesizing heterocyclic compounds such as flavones, flavanols, flavanones, etc. Chalcone has been synthesized using (E)-1-(4'-hydroxyphenyl)-3-(3-methoxyphenyl)prop-2-en-1-on with 1,4-dibromobutane. The structure of compounds were characterized based on spectroscopic data included UV-Vis, IR, and 1H-NMR. Compounds COB-Br showed high absorbance at 207, 226 and 318 nm. HPLC analysis showed a major peak at 20.37 min at 226 nm. IR spectroscopy showed a peak at 3011 cm-1 indicated the present of alkane C-H; a peak at 1650 cm-1 indicated the present of C = O group; a peak at 1605 cm-1 indicated the present of C = C alkenes; a peak at 1594 cm-1 indicated the presence of C = C aromatic, and a peak at 557 cm-1 indicated the presence of C-Br. 1H-NMR spectral analysis results showed that the number of obtained was in accordance with the expected structure. Chemical shifts at δ 7.55 and 7.77 respectively showed the doublet signal of proton Hα and Hβ while chemical shifts at δ 4.10; 2.10; 2.01 and 3.52 respectively show the triplet, multiplet, multiplet and triplet signals of proton from substituent 4-bromobutoxy

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

03 02. 117 (0081)

Penerbit

Pekanbaru : . Universitas Riau – FMIPA – Kimia., 2017

Deskripsi Fisik

v, 52 hlm.; ill.; 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

03 02. 117 (0081)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

DAUS

Versi lain/terkait

Lampiran Berkas

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