Multi-drug resistant organism (MDRO) is a microorganism (especially bacteries) that is already resistant to several antibiotic classes, making it difficult for patients to be treated. Cefoperazone-sulbactam is a combination of cefoperazone and sulbactam that has broad spectrum and known to be good antibacterial activity for Gram negative bacilli that produces ESBL and resistant to meropenem. Th…