CD Skripsi
Perbandingan Pengaruh Pemberian Suspensi Kedelai Dengan Suspensi Tempe Terhadap Kadar Trigliserida Serum Tikus Putih (Rattus Novergicus) Diabetik
Soybean isoflavone has insulinotropic effect, apart from its potent antioxidant effect. Fermentation process of soybean in the making of tempeh increases isoflavone bioavailability by changing the type of isoflavone into aglikan, and also by decreasing antinutrition and fitat acid level. The objective of this study was to compare serum triglyceride level from diabetic rat after administration of soybean and tempeh suspension. This experimental used Post-Test Only with Control Group design. There were 20 rats, Wistar strain, male distributed into 4 treatment groups: Standard (S), Negative Control (KN), Soybean Treatment (K1), and Tempeh Treatment (K2). Type 2 diabetes mellitus induced by combination of streptozotocin and nicotinamide with 50 mg/kgBW and 110 mg/kgBW doses respectively, intraperitonelly. Treated animal were given soybean suspension (200 mg/kgBW/day) and tempeh suspension (200 mg/kgBW/day) during 30 days periode with sonde. Serum triglyceride level was assessed by colorimetric enzymatic analysis with Glycerol-3-phosphate-oxidase. Data analyzed with One Way Anova (p0,05). In conclusion, there was no significant difference between soybean and tempeh suspension administration for serum triglyceride level in diabetic rats.
Keyword: Soybean, tempeh, triglyceride, type 2 diabetes mellitus.
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