CD Skripsi

Gambaran Histopatologi Substansia Nigra Mencit (Mus Musculus) Setelah Pemaparan Paraquat

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Paraquat is herbicides that have a high level of effectiveness in tackling weeds, but have toxic effects on human and environment. One of the toxic effects is decreased dopamine contents in brain. Purpose of this research was to know the effects of paraquat on the histopathology of substantia nigra of mice (Mus musculus). This was experimental research with post test design only with control and inlcuded 15 mices which were divided to control group, dose of mice given paraquat 25, 50, 75 and 100 mg/kgBody/day of paraquat for 7 days by spraying. The results showed increased glia cells and edema by giving paraquat with dose of 25, 50, 75 and 100 mg/kgBody. The study showed there was significant correlation between the damage of histopathology substantia nigra of mice with increased doses of paraquat exposure for 7 days (p=0.008). In conclusion, there are significant changes in substantia nigra overview of mice after paraquat exposure for 7 days. Keywords: brain, histopathology of substantia nigra, paraquat

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

08 01. 118 (0097)

Penerbit

Pekanbaru : Universitas Riau – Fakultas Kedokteran – Pendidikan Kedokteran., 2018

Deskripsi Fisik

xiv, 71 hlm.; ill.; 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

08 01. 118 (0097)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KEDOKTERAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

DAUS

Versi lain/terkait

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