CD Skripsi

Sintesis Dan Uji Toksisitas Dua Analog Kurkumin Dari Sikloheksanon Dengan Turunan Dimetoksibenzaldehid

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SUMMARY
Curcumin is one of secondary metabolites classified into the class of fenolic that are known to have biological activities such as anticancer, antidiabetic, anti-inflammatory and antioxidant. Curcumins become model of target compounds that have various structure. The curcumin analogue compounds of cyclohexanone derivate has been syntesized under microwave irradiation by using NaOH. The purity of all compounds has been tested by using TLC, melting point test and analytical HPLC. Then they are identified by using UV, IR, 1H-NMR and MS spectroscopy. Toxicity test was determined using Brine Shrimp Lethality Test (BSLT) method to Artemia Salina Leach. The rendement results of this research from (2E,6E)-2,6-bis(2,3-dimethoxybenzylidene)-cyclohexanone (DK1) and (2E,6E)-2,6-bis(3,4-dimethoxy benzylidene)-cyclohexanone (DK2) were 78,33% and 29,86% respectively. The toxicity test showed with value LC50 < 200 ppm. The results showed that DK1 and DK2 is not toxic that have LC50 > 200 ppm, were 18,578 ppm and 1,528 ppm, respectively.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

03 02. 116 (0014)

Penerbit

Pekanbaru : Universitas Riau – FMIPA – Kimia., 2016

Deskripsi Fisik

xiv, 57 hlm.: ill.: 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

03 02. 116 (0014)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

JAKA

Versi lain/terkait

Lampiran Berkas

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