Antidesma bunius is one of the species belonging to the Euphorbiaceae family. Three species of Antidesma, A. madagascariensis, A. ghaesembilla and A. venosum have been widely reported to have antibacterial activity. This study aims to isolate and characterize secondary metabolite compounds, and identify the antibacterial activity of ethyl acetate extract of A. bunius bonai leaves using the disc…