Sintesis Dan Uji Toksisitas Analog Pirazolin Dengan Inti Naftalen Dari 1-Ase…

ABSTRACT Pyrazoline is one of alkaloids that available in limited amount in nature, but it has biological activities for treatment of various diseases include cancer. Analogue compound of pyrazoline (PF CN1-2F) with naphthalene core has been synthesized from phenyl hydrazine and chalcone (CN1-2F). This chalcone is a condensation product beetwen 1-acetylnaphthalene and 2-fluorobenzaldehyde with…