Muntingia calabura is one of the natural plant that was popular in indonesia. This of the main ingredients of Muntingia calabura is flavonoids, tannins, glycosides, saponins, esesnsial oil, and that has antibacterial and antiinflammatory. This research was conducted in December 2019 - February 2020 at the Fish Parasites and Diseases Laboratory, Fisheries and Marine Faculty, Riau University.…