Sintesis Dan Uji Toksisitas Senyawa Analog Kurkumin 3,5-Bis((E)-Metoksi Benzi…

A study has been conducted to synthesize analog of curcumin with base catalyzed condensation of 4-piperidone hydrochloride with substituted benzaldehyde under reflux led the formation of mono-carbonyl curcumin. The synthesized curcumin were further reacted with benzosulphonyl chloride by nucleophilic substitution of –NH group to afford 3,5-bis((E)-2-metoksi benziliden)-1-(fenilsulfonil)piper…