SUMMARY Alstonia spatulata (pulai basung) is a plant of the Apocynaceae family that grows in the scrub area. This study aimed to isolate secondary metabolite compounds contained in the bark of this plant and to determine the toxicicity level of n-hexane, methanol and dichloromethane extracts and compound isolated. Phytochemical analysis showed that A. spatulata contains terpenoids and alkaloid…