Air is the most important need in the survival of all living things, especially humans. This study is a descriptive observational study with a longitudinal and time-series design, which aims to assess air quality in the PICU room of Arifin Achmad Hospital Riau Province. Measurements of CO2, O2, noise, and lighting levels were conducted in the morning, afternoon, and evening for 14 days. CO2 qua…