Sintesis Dan Uji Toksisitas Senyawa Pirazolin 5-(2-Fluorofenil)-3-(2-Naftalen…

ABSTRACT Pyrazoline is one of secondary metabolites from alkaloid and has many bioactivity such as anticancer and has high toxicity. Pyrazoline 5-(2- fluorophenyl)-3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazole (PH CN2-2F) can be synthesized by reacting chalcone (E)-3-(2-fluorophenyl)-1-(naphthalen-2-yl)prop- 2-enon (CN2-2F) and hydrazine hydrate using glacial acetic acid (CH3COOH) as cataly…