Hepatitis B virus (HBV) is a virus that can infect parenchyme. HBV is transmitted through percutaneous contact and body fluids exposure from hepatitis B patients. Previous studies have shown levels of anti-hepatitis B surface (anti-HBs) have decreased by 15-20 years after 3 doses of hepatitis B vaccine and genetic factors are thought to influence the decrease in anti-HBs titers. This study aime…