ABSTRACT Tumu Merah (Bruguiera gymnorrhiza) is a mangrove plant that can be used as food. The content of compounds such as alkaloids, flavonoids, phenols, terpenoids, steroids, and saponins can be used for antimicrobial, anticancer, and antileukemic properties. The purpose of this study was to test the effectiveness of mangrove leaf extract of B. gymnorrhiza in inhibiting the growth of S. …