ABSTRACT This study aims to determine the bioactive components of the sea grape (Caulerpa sp.) fraction qualitatively and to determine its antibacterial activity using the well method. In the extraction process, the solvent used is methanol with a ratio of sample: solvent 1:3(w/v). While solvent fraction is used there are 3 types, namely n-hexane, ethyl acetate and butanol with a ratio of …