Mangroves are plants that thrive in coastal areas that have very high potential for bioactive compounds, one of the type of mangrove is Bruguiera gymnorrhiza L. The purpose of this study was the isolation of secondary metabolites and toxicity tests using the BSLT (Brine Shrimp Lethality Test) method. Mangrove leaves were extracted by maceration method using ethanol and fractionated with n-…