Depression is a neuropsychiatric disorder that affects behavior, emotions, and thoughts in a negative direction. Nutmeg seed extract has the potential to be an antidepressant that has been tested in vivo and in silico. The results of in vivo tests using the forced swim tests (FST) method of double-test animals showed that 100 mg/kg of nutmeg n-hexane extract (ENHP) was able to reduce the im…