Chalcone or 1,3-diphenyl-2-propenone is a secondary metabolite compound of the open-chain flavonoid group with a ,β-unsaturated carbonyl framework structure which has various bioactivities, including anti-breast cancer. The morpholino- chalcone hybrid compound (E)-3-(2-methoxyphenyl)-1-(2-(2-morpholinoethoxy) naphthalene-1-yl)prop-2-en-1-one is named as 2OMP-2MOF-CLN (22) has been successfu…