Pyrazoline is known as a heterocyclic compound that has various biological activities such as antioxidant, antibacterial, antifungal, antimalarial, and anticancer. Pyrazoline is a five-ring heterocyclic compound with three carbon atoms and two adjacent nitrogen atoms. The various bioactivities of pyrazoline were caused by the presence of heteroatom. Pyrazoline analog, 5-(3- fluorophenyl)-3…